个人邮箱：chemlxc@163.com；QQ: 171399079
刘西成，男，1980.04，山东潍坊人，工学博士，副教授。主要从事无机化学、中级无机化学和无机化学实验的讲授工作；现主持山东省自然科学基金面上项目一项，近五年在Inorganic Chemistry，Inorganic Chemistry Frontiers，Dalton Transactions，Dyes and Pigments，Joural of Inorganic Biochemistry，Journal of Materials Chemistry C等国内外期刊上发表论文40余篇。
教育及工作经历：
2012/9 - 2016/6，天津大学，化工学院，工学博士
2002/9 - 2005/7，bv伟德国际体育，化学院，理学硕士
1998/9 - 2002/7，bv伟德国际体育，化学系，理学学士
研究方向：
小分子空穴传输材料的合成及其光电应用；
有机金属抗癌配合物的设计及诊疗一体化研究；
招生：硕士1-2名/年
招生专业：无机化学/有机化学/应用化工/化学生物学;
欢迎有理想、有追求的有志青年报考！
主持或参加科研项目：
[1] 山东省自然科学基金面上项目：溶酶体靶向铁-铱异核金属席夫碱类抗癌体系的构建及机理研究（ZR2020MB102），2021.01~2023.12；主持。
[2] 山东省高等学校科技计划项目：聚集诱导发光金属铱四苯乙烯抗癌体系的构建及其抗癌机理研究（J18KA082），2018.6~2021.5；主持。
[3] 国家自然科学基金面上项目：基于双模激发联动干预功能性分子探针的ROS&AOS协同应激微环境分析与评价（22174090），2022.01-2025.12；参与。
[4] 国家重点研发计划：“印刷OLED显示关键材料与器件技术”(2016YFB0401300)；2016~2021年；参与。
[5] 国家高技术研究发展计划（863计划）：“柔性AMOLED显示材料产业化关键技术研究”（2015AA033402）；2015~2017年；参与。
指导大学生获奖及科研训练情况：
[1] 国家级大学生创新创业训练计划项目：含三苯胺基团环铱配合物的合成及抗癌性能研究（201710446042），指导（优秀结题）。
[2] 国家级大学生创新创业训练计划项目：三苯胺修饰的荧光型金属铱(III)双聚体的合成及抗肿瘤应用（S202010446011），指导（已结题）。
[3] 省级大学生创新创业训练计划项目：溶酶体靶向金属铱香豆素抗癌体系的构建（S201910446046），2019.10-2021.5；指导（已结题）。
[4] 校级大学生创新创业训练计划项目：铁-铱混合金属配合物抗癌体系的构建及生物性能研究（2018A043），2018.10 ~ 2020.5；指导（已结题）。
[5] 校级优秀本科毕业论文 唐艳华 2019
奖励情况:
2019年度山东省高等学校科学技术奖 叁等奖（第二位）
bv伟德国际体育2019年青年教师教学比赛 校级二等奖
代表性研究成果：
2023年度
[1] Jinfeng Liu*, Yuting Wu a, Ge Yang, Zhe Liu* , Xicheng Liu*, Mitochondrial targeting half-sandwich iridium(III) and ruthenium(II) dppf complexes and in vitro anticancer assay, Journal of Inorganic Biochemistry, 2023,239, 112069
[2] Liyan Wang, Xicheng Liu*, Yuting Wu, Xian He, Xiaohui Guo, Wenshan Gao, Lin Tan, Xiang-Ai Yuan, Jinfeng Liu, and Zhe Liu*, In Vitro and In Vivo Antitumor Assay of Mitochondrially Targeted Fluorescent Half-Sandwich Iridium(III) Pyridine Complexes, Inorganic Chemistry, 2023, doi.org/10.1021/acs.inorgchem.2c03333
2022年度
[1] Qiaochu Li , Mingxiao Shao , Weiguang Ran, Xinzhuo Sun, Huiying Liu, Qi Wang, Xicheng Liu*, Laijin Tian, Guang Chen, Zhe Liu*, An AIE-featured triphenyltin(IV)-triphenylamine acylhydrazone compound and anticancer application, Dyes and Pigments, 2022, 201, 110231
[2] Ruixi Xu, Yuting Wu, Zhe Liu*, Jinfeng Liu and Xicheng Liu*, Lysosomal Targeted Cyclometallic Iridium(Ⅲ) Salicylaldehyde-Coumarin Schiff Base Complexes and Anticancer Application, Frontiers in Chemistry, 2022, 10, 906954
[3] Yuting Wu, Jinfeng Liu* , Mingxiao Shao , Pei Zhang, Shaohua Song, Ge Yang, Xicheng Liu*, Zhe Liu*, Cyclometalated iridium(III) dithioformic acid complexes as mitochondria-targeted imaging and anticancer agents, Journal of Inorganic Biochemistry 2022, 233, 111855
[4] Zihan Wang, Zexuan Lv, Xicheng Liu*, Yuting Wu, Jiaying Chang, Ruixiao Dong, Caiyue Li, Xiang-Ai Yuan, Zhe Liu*, Anticancer application of ferrocene appended configuration-regulated half-sandwich iridium(III) pyridine complexes, Journal of Inorganic Biochemistry 2022, 237, 112010
[5] 刘西成，刘哲，刘聪，赵潇涵，郑梦霄，一种香豆素修饰的荧光型环铱()配合物及其制备方法和应用，2022-02-15，专利号：ZL202010625405.X，授权公告号：CN111646966B
2021年度
[1] Mingxiao Shao,† Meimei Yao,† Xicheng Liu*, Chao Gao, Weiyan Liu, Jinghang Guo, Jiawen Zong, Xinzhuo Sun, and Zhe Liu*, In Vitro and In Vivo of Triphenylamine-Appended Fluorescent HalfSandwich Iridium(III) Thiosemicarbazones Antitumor Complexes, Inorganic Chemistry, 2021, 60, 17063−17073.
[2] Liyan Wang, Chenyang Huang, Fenglian Hu, Wen Cui, Yiqing Li, Jingwen Li, Jiawen Zong, Xicheng Liu*, Xiang-Ai Yuan and Zhe Liu*, Preparation and antitumor application of N-phenylcarbazole/triphenylamine-modified fluorescent half-sandwich iridium(III) Schiff base complexes, Dalton Transactions, 2021, 50, 15888.
[3] Xicheng Liu*, Mingxiao Shao, Congcong Liang, Jinghang Guo, Guangxuan Wang, Xiang-Ai Yuan, Zhihong Jing, Laijin Tian, Zhe Liu*, Preparation and bioactivity of iridium(III) phenanthroline complexes with halide ions and pyridine leaving groups, ChemBioChem, 2021, 22, 557-564.
[4] 刘西成 刘哲 邵明晓 张莹 谢瑶琪 一种溶酶体靶向的荧光型金属铱双聚体及其制备方法和应用，2021-9-24，专利号：ZL 2020 1 0111378.4，授权公告号：CN 111217732 B
2020年度
[1] Shujiao Chen, Xicheng Liu*, Xingxing Ge, Qinghui Wang, Yaoqi Xie, Yingying Hao, Ying Zhang, Lei Zhang, Wenjing Shang, Zhe Liu*, Lysosome-targeted iridium(III) compounds with pyridine-triphenylamine Schiff base ligands: Syntheses, antitumor application and mechanism, Inorganic Chemistry Frontiers, 2020, 7, 91–100.
[2] Xicheng Liu*, Shujiao Chen, Xingxing Ge, Ying Zhang, Yaoqi Xie, Yingying Hao, Daiqun Wu, Jinmin Zhao, Xiang-Ai Yuan, Laijin Tian, Zhe Liu*, Dual functions of Iridium(III) 2-phenylpyridine complexes: metastasis inhibition and lysosomal damage, Joural of Inorganic Biochemistry, 2020, 205, 110983
[3] Bin Wang, Xicheng Liu, Peiwei Gong, Xingxing Ge, Zhe Liu and Jinmao You, Fluorescent COFs with a highly conjugated structure for visual drug loading and responsive release, Chemical Communications, 2020, 56, 519-522.
[4] Cong Liu, Xicheng Liu*, Xingxing Ge, Qinghui Wang, Lei Zhang, Wenjing Shang, Yue Zhang, XiangAi Yuan, Laijin Tian, Zhe Liu*, Jinmao You, Fluorescent iridium(III) coumarin-salicylaldehyde Schiff base compounds as Lysosome-Targeted antitumor agents, Dalton Transactions, 2020, 49, 5988–5998
[5] Xicheng Liu, Yali Han, Xingxing Ge and Zhe Liu, Imidazole and Benzimidazole Modified Half-Sandwich IridiumIII N-Heterocyclic Carbene Complexes: Synthesis, Anticancer Application, and Organelle Targeting, Frontiers in Chemistry, 2020, 8, 182
[6] Lexing Chen, Zhengwei Wang, Tongguang Qiu, Ruikun Sun, Zhiyuan Zhao, Laijin Tian*, Xicheng Liu*，Synthesis, structural characterization and properties of triorganotin complexes of Schiff base derived from 3-aminobenzoic acid and salicylaldehyde or 2,4-pentanedione，Applied Organometallic Chemistry, 2020, 34: e5790
[7] Shujiao Chen, Xicheng Liu*, Jie Huang*, Xingxing Ge, Qinghui Wang, Meimei Yao, Yue Shao, Tong Liu, Xiang-Ai Yuan, Laijin Tian, Zhe Liu*，Triphenylamine/carbazole-modified Ruthenium(II) Schiff base compounds: Synthesis, biological activity and organelle targeting，Dalton Transactions, 2020, 49, 8774–8784.
[8] Mingxiao Shao, Xicheng Liu*, Yiwei Sun, Shuaihua Dou, Qi Chen, Xiang-Ai Yuan, Laijin Tian, Zhe Liu*, Preparation and anticancer mechanism of configuration-controlled Fe(II)-Ir(III) heteronuclear metal complexes, Dalton Transactions, 2020, 49, 12599–12609.
2019年度
[1] Xicheng Liu*, Xiangdong He, Xiaojing Zhang, Yongling Wang, Jiaying Liu, Xiujuan Hao, Yue Zhang, Xiang-Ai Yuan, Laijin Tian, Zhe Liu*, Synthesis and Antineoplastic Applications of TPE Appended Organometallic Iridium(III) Complexes, ChemBioChem, 2019, 20, 2767 – 2776
[2] Xicheng Liu*, Hailong Hao, Xingxing Ge, Xiangdong He, Yifei Liu, Yan Wang, Haojie Wang, Mingxiao Shao, Zhihong Jing, Laijin, Tian, Zhe Liu*, Triphenylamine-appended cyclometallated iridium(III) complexes: Preparation, photophysical properties and application in biology/luminescence imaging, Joural of Inorganic Biochemistry, 2019, 199, 110757.
[3] Xicheng Liu*, Yanhua Tang, Xiangdong He, Xingxing Ge, Jiao Liu, Xiaoyu Meng, Mingxiao Shao, Yingmin Jin, Laijin Tian*, Zhe Liu*, Triphenyltin(IV) acylhydrazone compounds: Synthesis, structure and bioactivity, Journal of Inorganic Biochemistry, 2019, 191, 194–202.
[4] Liu Xi-Cheng, Liu Xin-Yu, Zhou Ping, Li Jin-Jie, Tian Hao-Ze, Li Xiang-Gao*, Synthesis, Characterization and Properties of Bipolar Triphenylamine Charge Transport Materials, Chinese Joural of Structural Chemistry, 2019, 38, 533-540.
[5] Xiangdong He, Xicheng Liu*, Yanhua Tang, Jiuyao Du, Meng Tian, Zhishan Xu, Xinyu Liu, Zhe Liu*, Half-sandwich Iridium(III) complexes with triphenylamine-substituted dipyridine frameworks and bioactivity applications, Dyes and Pigments, 2019, 160, 217–226.
[6] Xingxing Ge, Shujiao Chen, Xicheng Liu*, Qinghui Wang, Lijun Gao, Chengfeng Zhao, Lei Zhang, Mingxiao Shao, Xiang-Ai Yuan, Laijin Tian, Zhe Liu*，Ferrocene-Appended Iridium(III) Complexes: Configuration Regulation, Anticancer Application and Mechanism Research, Inorganic Chemistry, 2019, 58, 14175−14184.
[7] Juanjuan Li, Xicheng Liu*, Haifeng Zhang, Xingxing Ge, Yanhua Tang, Zhishan Xu, Laijin Tian, Xiangai Yuan, Xudong Mao, and Zhe Liu*, Ferrocenyl-Triphenyltin Complexes as Lysosome-Targeted Imaging and Anticancer Agents, Inorgnic Chemistry, 2019, 58, 1710−1718.
[8] Shujiao Chen, Xicheng Liu*, Zhenzhen Tian, Xingxing Ge, Hailong Hao, Yingying Hao, Ying Zhang, Yaoqi Xie, Laijin Tian, Zhe Liu*，Triphenylamine and carbazole-modified iridiumIII 2-phenylpyridine complexes: Synthesis, anticaner application and targeted research, Applied Organometallic Chemistry, 2019, e5053
[9] Xingxing Ge, Xicheng Liu*, Zhenzhen Tian, Shujiao Chen, Xinyu Liu, Lihua Guo, Peiwei Gong, Baoping Ling, Xiang-Ai Yuan, Zhe Liu*, Half-sandwich Ruthenium(II) complexes with triphenylamine modified dipyridine skeleton and application in biology/luminescence imaging, Applied Organometallic Chemistry, 2019, e5171.
[10] Hailong Hao, Xicheng Liu*, Xingxing Ge, Yao Zhao, Xue Tian, Ting Ren, Yan Wang, Chengfeng Zhao, Zhe Liu, Half-sandwich iridium(III) complexes with α-picolinic acid frameworks and antitumor applications, Journal of Inorganic Biochemistry, 2019, 192, 52–61.
[11] Yichao Lin, Minghui Guo, Jin Liu, Laijin Tian* and Xicheng Liu*, Synthesis and structural characterization of the complexes of 2-(menthoxycarbonyl)ethyltin chloride, Main Group Met. Chem. 2019; 42: 37–45.
[12] Jin Liu, Yichao Lin, Min Liu, Shiqing Wang, Yuxiao Li, Xicheng Liu*, Laijin Tian*, Synthesis, structural characterization and cytotoxic activity of triorganotin 5-(salicylideneamino)salicylates, Appl Organometal Chem. 2019, 33, 4715.
[13] Yichao Lin, Wugai An, Xingxing Ge, Mingzhu Liu, Yue Wang, Xicheng Liu*, Laijin Tian*, Synthesis, characterization and cytotoxic activity of diorganotin complexes with Schiff base derived from salicylaldehyde and l-tyrosine, Joural of Coordination Chemistry, 2019, 72, 987-1001.
[14] Tian Lai-Jin*, Chen Le-Xing, An Wu-Gai, Liu Xi-Cheng*, Diorganotin Complexes of N-[4-(Diethylamino)salicylidene]-(L)-tryptophane: Syntheses, Structures and Properties, Chinese J. Struct. Chem., 2019, 38, 1977-1985.
2018年度
[1] Xiangdong He, Meng Tian, Xicheng Liu*, Yanhua Tang, Chang Fang Shao, Peiwei Gong, Jinfeng Liu, Shumiao Zhang, Lihua Guo, and Zhe Liu*, Triphenylamine-Appended Half-Sandwich Iridium(III) Complexes and Their Biological Applications, Chemistry-An Asian Joural, 2018, 13, 1500-1509.
[2] Yali Han, Zhenzhen Tian, Shumiao Zhang, Xicheng Liu*, Juanjuan Li, Yanru Li, Yi Liu, Min Gao, Zhe Liu*, Half-sandwich IridiumIII N-heterocyclic carbene antitumor complexes and biological applications, Journal of Inorganic Biochemistry, 2018, 189, 163-171.
[3] Yali Han, Xicheng Liu, Zhenzhen Tian, Xingxing Ge, Juanjuan Li, Min Gao, Yanru Li, Yi Liu, Zhe Liu*, Half-sandwich Iridium(III) Benzimidazole-Appended Imidazolium Based N-heterocyclic Carbene Complexes and Antitumor Application, Chemistry-An Asian Joural, 2018, 13, 3697–3705.
2017年以前
[1] Xicheng Liu, Fei Zhang, Zhe Liu, Yin Xiao, Shirong Wang and Xianggao Li*, Dopant-free and low-cost molecular ‘‘bee’’ hole-transporting materials for efficient and stable perovskite solar cells, Journal of Materials Chemistry C, 2017, 5, 11429-11435.
[2] Liu Xicheng, Zhu Lifeng, Zhang Fei, You Jing, Xiao Yin, Li Dongmei, Wang Shirong, Meng Qingbo, Li Xianggao, Stable non-doping perovskite solar cells based on hydrophobic triphenylamine hole-transporting materials, Energy Technology, 2017, 5, 312 – 320.
[3] Liu Xicheng, You Jing, Xiao Yin, Wang Shirong, Gao Wenzheng, Peng Junbiao and Li Xianggao, Film-forming hole transporting materials for high brightness flexible organic light-emitting diodes, Dyes and Pigments, 2016, 125: 36-43.
[4] Liu Xicheng, Liang Junfei, You Jing, Ying Lei, Xiao Yin, Wang Shirong and Li Xianggao, Small molecular hole-transporting and emitting materials for hole-only green organic light-emitting devices, Dyes and Pigments, 2016, 131: 41-48.
[5] Zhang Fei#, Liu Xicheng#, Yi Chenyi, Bi Dongqin, Luo Jingshan,Wang Shirong*, Li Xianggao*, Xiao Yin, Zakeeruddin Shaik Mohammed*, Grätzel Michael*, Dopant-Free Donor (D)-p-D-p-D Conjugated HoleTransport Materials for Efficient and Stable Perovskite Solar Cells, ChemSusChem, 2016, 9, 2578–2585.
